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Human Mothers against decapentaplegic homolog 9 (SMAD9) ELISA Kit

Human Mothers against decapentaplegic homolog 9 (SMAD9) ELISA Kit

Cat no: KTE60570

Supplier: Abbkine Scientific Co.Ltd.
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SMAD9 or Mothers against decapentaplegic homolog 9 is a polypeptide that, as its name describes, is a homolog of the Drosophila gene: "Mothers against decapentaplegic". It belongs to the SMAD family of proteins, which belong to the TGF? superfamily of modulators. Like many other TGF? family members, SMAD9 is involved in cell signalling. When a bone morphogenetic protein binds to a receptor (BMP type 1 receptor kinase) it causes SMAD9 to interact with SMAD anchor for receptor activation (SARA).The binding of ligands causes the phosphorylation of the SMAD9 protein and the dissociation from SARA and the association with SMAD4. It is subsequently transferred to the nucleus where it forms complexes with other proteins and acts as a transcription factor
Catalogue number: KTE60570
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: O15198
Gene: 4093
Additional info: Human Mothers against decapentaplegic homolog 9 (SMAD9) ELISA Kit has high sensitivity and excellent specificity for detection of Human SMAD9. No significant cross-reactivity or interference between Human SMAD9 and analogues was observed.

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