Human Muscle Skeletal Receptor Tyrosine Kinase antibody (MUSK-Ab) ELISA Kit

Cat no: KTE62475

Supplier: Abbkine Scientific Co.Ltd.

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MuSK (for Muscle Specific Kinase) is a receptor tyrosine kinase required for the formation of the neuromuscular junction. It is activated by a nerve-derived proteoglycan called agrin. This protein binds to several receptors on the surface of skeletal muscle. The receptor which seems to be required for formation of the neuromuscular junction (NMJ), which comprises the nerve-muscle synapse is called MuSK (Muscle specific kinase). MuSK is a receptor tyrosine kinase - meaning that it induces cellular signaling by causing the addition of phosphate molecules to particular tyrosines on itself, and on proteins which bind the cytoplasmic domain of the receptor.In mice which are deficient for either agrin or MuSK, the neuromuscular junction does not form. Many other proteins also comprise the NMJ, and are required to maintain its integrity.

Catalogue number:	KTE62475
Reactivities:	Human
Applications:	ELISA
Size:	48T, 96T, 96T5, 96T50
Additional info:	Human Muscle Skeletal Receptor Tyrosine Kinase antibody (MUSK-Ab) ELISA Kit has high sensitivity and excellent specificity for detection of Human MUSK-Ab. No significant cross-reactivity or interference between Human MUSK-Ab and analogues was observed.

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Human Muscle Skeletal Receptor Tyrosine Kinase antibody (MUSK-Ab) ELISA Kit

Cat no: KTE62475

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