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Human Myomegalin (PDE4DIP) ELISA Kit

Human Myomegalin (PDE4DIP) ELISA Kit

Cat no: KTE61274

Supplier: Abbkine Scientific Co.Ltd.
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By analyzing ESTs for cardiac muscle-specific transcripts, followed by screening heart cDNA libraries and 5-prime RACE, Soejima et al. (2001) cloned 4 splice variants of PDE4DIP, which they called MMGL. The variant-1 transcript has a long 3-prime untranslated region containing 9 possible polyadenylation signals, and it encodes a deduced 174-amino acid protein. Variants 2, 3, and 4 encode proteins of 174, 173, and 240 amino acids, respectively. Northern blot analysis detected high expression of a 1.0- to 1.3-kb band and lower expression of 4.4- and 8.5-kb bands in adult and fetal heart, skeletal muscle, and all specific heart regions examined. Only the 4.4-kb transcript was detected in aorta. Fluorescence-tagged variants 1 and 4 were expressed in both the cytoplasm and nucleus of transfected mouse myocytes.
Catalogue number: KTE61274
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: Q5VU43
Gene: 653513
Additional info: Human Myomegalin (PDE4DIP) ELISA Kit has high sensitivity and excellent specificity for detection of Human PDE4DIP. No significant cross-reactivity or interference between Human PDE4DIP and analogues was observed.

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