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Human NAD-dependent deacetylase sirtuin-1 (SIRT1/SIR2L1) ELISA Kit

Human NAD-dependent deacetylase sirtuin-1 (SIRT1/SIR2L1) ELISA Kit

Cat no: KTE62649

Supplier: Abbkine Scientific Co.Ltd.
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Sirtuin 1 is a member of the sirtuin family of proteins, homologs of the Sir2 gene in S. cerevisiae. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family.Sirtuin 1 is downregulated in cells that have high insulin resistance and inducing its expression increases insulin sensitivity, suggesting the molecule is associated with improving insulin sensitivity.
Catalogue number: KTE62649
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: Q96EB6
Gene: 23411
Additional info: Human NAD-dependent deacetylase sirtuin-1 (SIRT1/SIR2L1) ELISA Kit has high sensitivity and excellent specificity for detection of Human SIRT1. No significant cross-reactivity or interference between Human SIRT1 and analogues was observed.

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