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Human Nesprin-2 (SYNE2) ELISA Kit

Cat no: KTE60415


Supplier: Abbkine Scientific Co.Ltd.
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SYNE2 is a nuclear outer membrane protein that binds cytoplasmic F-actin. This binding tethers the nucleus to the cytoskeleton and aids in the maintenance of the structural integrity of the nucleus. Several transcript variants encoding different isoforms have been found for this gene. SYNE2 contains multiple spectrin repeats and a 60-amino acid C-terminal region homologous to the Drosophila protein Klarsicht. RT-PCR analysis showed low to moderate expression of 2 SYNE2 splice variants in most tissues examined, including skeletal and cardiac muscle, kidney, liver, pancreas, and placenta, and indicated that alternative splicing patterns are conserved between SYNE1 and SYNE2.Nesprin-2-gamma also has a bipartite nuclear localization signal and a leucine zipper motif.
Catalogue number: KTE60415
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: Q8WXH0
Gene: 23224
Additional info: Human Nesprin-2 (SYNE2) ELISA Kit has high sensitivity and excellent specificity for detection of Human SYNE2. No significant cross-reactivity or interference between Human SYNE2 and analogues was observed.

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