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Human Neuroendocrine convertase 2 (PCSK2) ELISA Kit

Human Neuroendocrine convertase 2 (PCSK2) ELISA Kit

Cat no: KTE61287

Supplier: Abbkine Scientific Co.Ltd.
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Proprotein convertase 2 is a serine protease and proprotein convertase PC2, like proprotein convertase 1 (PC1), is an enzyme responsible for the first step in the maturation of many neuroendocrine peptides from their precursors, such as the conversion of proinsulin to insulin intermediates. To generate the bioactive form of insulin (and many other peptides), a second step involving the removal of C-terminal basic residues is required; this step is mediated by carboxypeptidases E and/or D. PC2 plays only a minor role in the first step of insulin biosynthesis, but a greater role in the first step of glucagon biosynthesis compared to PC1. PC2 binds to the neuroendocrine protein named 7B2, and if this protein is not present, proPC2 cannot become enzymatically active.
Catalogue number: KTE61287
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: P16519
Gene: 5126
Additional info: Human Neuroendocrine convertase 2 (PCSK2) ELISA Kit has high sensitivity and excellent specificity for detection of Human PCSK2. No significant cross-reactivity or interference between Human PCSK2 and analogues was observed.

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