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Human Neuroserpin (SERPINI1) ELISA Kit

Human Neuroserpin (SERPINI1) ELISA Kit

Cat no: KTE60688

Supplier: Abbkine Scientific Co.Ltd.
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Serine protease inhibitors of the serpin superfamily are involved in many cellular processes. Neuroserpin was first identified as a protein secreted from the axons of dorsal root ganglion neurons. It is a member of the serpin superfamily of serine proteinase inhibitors. Neuroserpin is primarily secreted by axons in the brain, and preferentially reacts with and inhibits tissue-type plasminogen activator. It is thought to play a role in the regulation of axonal growth and the development of synaptic plasticity. Mutations in this gene result in familial encephalopathy with neuroserpin inclusion bodies (FENIB), which is a dominantly inherited form of familial encephalopathy and epilepsy characterized by the accumulation of mutant neuroserpin polymers. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Catalogue number: KTE60688
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: Q99574
Gene: 5274
Additional info: Human Neuroserpin (SERPINI1) ELISA Kit has high sensitivity and excellent specificity for detection of Human SERPINI1. No significant cross-reactivity or interference between Human SERPINI1 and analogues was observed.

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