Human Next to BRCA1 gene 2 protein (NBR2) ELISA Kit

Cat no: KTE61352

Supplier: Abbkine Scientific Co.Ltd.

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NBR2 (Neighbor Of BRCA1 Gene 2 (Non-Protein Coding)) is an RNA Gene, and is affiliated with the non-coding RNA class. NBR2 was identified by its close proximity on chromosome 17 to tumor suppressor gene BRCA1. Experimental evidence indicates that the two genes share a bi-directional promoter. Transcription for either gene is controlled individually by distinct transcriptional repressor factors. A short (112 amino acid) open reading frame is observed which includes a region derived from a LINE1 element. A strong Kozak signal is not observed for the putative ORF and the stop codon is more than 55 nucleotides upstream of the last splice site for the transcript, suggesting that the transcript is subject to nonsense-mediated decay. Therefore, this gene does not appear to encode a protein. Glucose starvation induces the expression of this gene and the long non-coding RNA transcribed by it functions with AMP-activated protein kinase in mediating the energy stress response.

Catalogue number:	KTE61352
Reactivities:	Human
Applications:	ELISA
Size:	48T, 96T, 96T5, 96T50
Accession:	O15453
Additional info:	Human Next to BRCA1 gene 2 protein (NBR2) ELISA Kit has high sensitivity and excellent specificity for detection of Human NBR2. No significant cross-reactivity or interference between Human NBR2 and analogues was observed.

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Human Next to BRCA1 gene 2 protein (NBR2) ELISA Kit

Cat no: KTE61352

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