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Human Osteopontin (OPN) ELISA Kit

Cat no: KTE60342

Human Osteopontin (OPN) ELISA Kit

Osteopontin (OPN), is a secreted multifunctional glyco-phosphoprotein with roles in bone metabolism, immune regulation, tissue remodeling , cell survival, and tumor progression . Gene structure and chromosomal location identify OPN as a member of the small integrin-binding ligand N-linked glycoprotein (SIBLING) family that also includes BSP,BMP1,DSPP, ENAM and MEPE. Murine OPN issynthesized as a 294 amino acid (aa) precursor protein with a predicted 16 aa signal peptide and a highly unusual mature protein sequence, containing 68 acidic aa and 23 potential Ser/Thr phosphorylation sites. Although the predicted molecular weight of OPN is 31 kDa,phosphorylation and N- and O-glycosylation may allow it to appear as large as 75 kDa. Variability in post-translational modifications can influence the activity of OPN.

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SPECIFICATIONS

Catalog Number

KTE60342

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

6696

Accession

P10451

Additional Info

Human Osteopontin (OPN) ELISA Kit has high sensitivity and excellent specificity for detection of Human SPP1. No significant cross-reactivity or interference between Human SPP1 and analogues was observed.

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