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Human P16 (5A8A) Antibody
ABBIOTEC

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ABBIOTEC

Cat no: 252710

Human P16 (5A8A) Antibody

CDK4I or p16-INK4 (Cyclin-dependent kinase 4 inhibitor A) is a negative regulator of the proliferation of normal cells. It is interacting strongly with CDK4 and CDK6 and by subsequently inhibiting their interaction with cyclins D and retinoblastoma protein phosphorylation. Defects in p16-INK4 are involved in tumor formation in a wide range of tissues. These defects cause cutaneous malignant melanoma 2 (CMM2), familial atypical multiple mole melanoma-pancreatic carcinoma syndrome,Mouse,elanoma-astrocytoma syndrome and Li-Fraumeni syndrome.

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SPECIFICATIONS

Catalog Number

252710

Size

0.1 mg

Applications

IHC

Reactivities

Hum

Format

Each vial contains 0.1 mg IgG in PBS pH7.4 with 0.03% sodium azide. Antibody was purified by Protein-G affinity chromatography.

P Type

Mouse Monoclonal Antibody

Antigen

Purified recombinant fragment of P16 e, Xenopus/Amphibian,pressed in E. coli.

Isotype

Mouse IgG1

Accession

P42771

Clonality

5A8A4,3G8D12

Additional Info

Human P16; P16; Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3; cyclin-dependent kinase inhibitor A; CDK4I; p16-INK4a; p16INK4A; p16-INK4; multiple tumor suppressor 1; MTS-1; CDKN2A; CDKN2; MTS1

SUPPLIER INFO

ABBIOTEC

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