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Human Paired mesoderm homeobox protein 2 (PRRX2) ELISA Kit

Cat no: KTE61114

Human Paired mesoderm homeobox protein 2 (PRRX2) ELISA Kit

PRRX2 is a member of the paired family of homeobox proteins. Expression is localized to proliferating fetal fibroblasts and the developing dermal layer, with downregulated expression in adult skin. Increases in expression of this gene during fetal but not adult wound healing suggest a possible role in mechanisms that control mammalian dermal regeneration and prevent formation of scar response to wounding. The composite 813-nucleotide cDNA encodes a putative 164-amino acid protein with 74% overall identity to mouse Prx2, showing high conservation in the homeodomain and extreme 3-prime region. PRX2 is expressed as a single 1.3-kb transcript. PRX2 is more strongly expressed in normal fetal than in adult skin, much more strongly expressed in both fetal and adult proliferating fibroblasts, and not expressed in keratinocytes.

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SPECIFICATIONS

Catalog Number

KTE61114

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

51450

Accession

Q99811

Additional Info

Human Paired mesoderm homeobox protein 2 (PRRX2) ELISA Kit has high sensitivity and excellent specificity for detection of Human PRRX2. No significant cross-reactivity or interference between Human PRRX2 and analogues was observed.

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