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Human Parathyroid Hormone Related Protein (PTHrP) ELISA Kit

Human Parathyroid Hormone Related Protein (PTHrP) ELISA Kit

Cat no: KTE61063

Supplier: Abbkine Scientific Co.Ltd.
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Parathyroid hormone-related protein (or PTHrP) is a protein occasionally secreted by cancer cells (breast cancer, certain types of lung cancer including squamous cell carcinoma). However, it also has normal functions. PTHrP acts as an endocrine, autocrine/ paracrine, and intracrine hormone. PTHrP is related in function to the "normal" parathyroid hormone. When a tumor secretes PTHrP, this can lead to hypercalcemia. As this is sometimes the first sign of the malignancy, hypercalcemia caused by PTHrP is considered a paraneoplastic phenomenon. PTHrP shares the same N-terminal end as parathyroid hormone and therefore it can bind to the same receptor (the Type I PTH receptor). PTHrP aids in normal mammary gland development and lactation as well as placental transfer of calcium.
Catalogue number: KTE61063
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: P12272
Gene: 5744
Additional info: Human Parathyroid Hormone Related Protein (PTHrP) ELISA Kit has high sensitivity and excellent specificity for detection of Human PTHLH. No significant cross-reactivity or interference between Human PTHLH and analogues was observed.

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