Human Pentosidine (PTD) ELISA Kit

Pentosidine is a well characterized and easily detected member of this large class of compounds. AGEs are biochemicals formed continuously under normal circumstances, but more rapidly under a variety of stresses, especially oxidative stress and hyperglycemia. They serve as markers of stress and act as toxins themselves. Pentosidine is typical of the class, except that it fluoresces, which allows it to be seen and measured easily. Because it is well characterized, it is often studied to provide new insight into the biochemistry of AGE compounds in general. Derived from ribose, a pentose, pentosidine forms fluorescent cross-links between the arginine and lysine residues in collagen. It is formed in a reaction of the amino acids with the Maillard reaction products of ribose. In patients with Diabetes mellitus type 2, pentosidine correlates with the presence and severity of diabetic complications.

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SPECIFICATIONS

Catalog Number

KTE61250

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Additional Info

Human Pentosidine (PTD) ELISA Kit has high sensitivity and excellent specificity for detection of Human PTD. No significant cross-reactivity or interference between Human PTD and analogues was observed.