Human Peroxisomal testis-specific protein 1 (PXT1) ELISA Kit

Genes reported to be crucial for spermatogenesis are often exclusively expressed in the testis. The putative amino acid sequence encoded by the cDNA of the Pxt1 gene contains a conserved Asn-His-Leu (NHL)-motif at its C-terminal end, which is characteristic for peroxisomal proteins. Pxt1-EGFP fusion protein is co-localized with known peroxisomal marker proteins in transfected NIH3T3 cells. The peroxisomal targeting signal NHL is functional and responsible for the correct subcellular localization of the Pxt1-EGFP fusion protein. In male germ cells peroxisomes were reported only in spermatogonia. The Pxt1 gene is so far the first gene coding for a putative peroxisomal protein which is expressed in later steps of spermatogenesis, namely in pachytene spermatocytes.

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SPECIFICATIONS

Catalog Number

KTE61025

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

222659

Accession

Q8NFP0

Additional Info

Human Peroxisomal testis-specific protein 1 (PXT1) ELISA Kit has high sensitivity and excellent specificity for detection of Human PXT1. No significant cross-reactivity or interference between Human PXT1 and analogues was observed.