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Human Pescadillo homolog (PES1) ELISA Kit

Human Pescadillo homolog (PES1) ELISA Kit

Cat no: KTE61247

Supplier: Abbkine Scientific Co.Ltd.
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PES1 is abnormally elevated in malignant tumors of astrocytic origin. It is a strongly conserved gene containing a BRCT domain that is essential for the activity of this gene product. The gene plays a crucial role in cell proliferation and may be necessary for oncogenic transformation and tumor progression.The deduced 588-amino acid PES1 protein is 74% identical to the zebrafish sequence. The authors noted the presence of a highly acidic region at the C terminus and that the protein has an alpha-helix structure. Immunoblot analysis showed that PES1 is expressed as an unmodified 72-kD protein and a SUMO1-modified 92-kD protein. In situ hybridization analysis revealed wide and high expression of Pes1 in embryonic mouse brain and spinal cord. Pes1 expression was upregulated in malignant, late-passage mouse astrocytes.
Catalogue number: KTE61247
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: O00541
Gene: 23481
Additional info: Human Pescadillo homolog (PES1) ELISA Kit has high sensitivity and excellent specificity for detection of Human PES1. No significant cross-reactivity or interference between Human PES1 and analogues was observed.

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