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Human Phosphatase and actin regulator 1 (PHACTR1) ELISA Kit

Cat no: KTE61223

Human Phosphatase and actin regulator 1 (PHACTR1) ELISA Kit

The PHACTR proteins share highest similarity in sequences surrounding the N- and C-terminal RPEL repeats and in the C-terminal actin- and PP1-binding domains. In situ hybridization of rat brain showed enrichment of Phactr1 in cerebral cortex, hippocampus, olfactory tubercle, nucleus accumbens, caudate-putamen, and piriform cortex.\nEndogenous PP1 coprecipitated with ectopically expressed rat Phactr1 in human embryonic kidney cells. Phactr1 also coprecipitated with actin in rat brain lysates. Yeast 2-hybrid analysis of a series of Phactr1 C-terminal truncation mutants indicated that PP1 bound to Phactr1 near the C terminus, while actin bound in a region containing RPEL repeats 2 and 3.

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SPECIFICATIONS

Catalog Number

KTE61223

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

221692

Accession

Q9C0D0

Additional Info

Human Phosphatase and actin regulator 1 (PHACTR1) ELISA Kit has high sensitivity and excellent specificity for detection of Human PHACTR1. No significant cross-reactivity or interference between Human PHACTR1 and analogues was observed.

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