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Human Phosphatidylinositol-glycan biosynthesis class F protein (PIGF) ELISA Kit

Human Phosphatidylinositol-glycan biosynthesis class F protein (PIGF) ELISA Kit

Cat no: KTE61212

Supplier: Abbkine Scientific Co.Ltd.
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PIGF encodes 1 of the enzymes involved in glycosylphosphatidylinositol (GPI) anchor biosynthesis. The primary biochemical defect in paroxysmal nocturnal hemoglobinuria (PNH), an acquired hematologic disorder with protean clinical manifestations including recurrent episodes of hemolysis, infections, and venous thrombosis, involves defective synthesis of GPI anchors that attach certain proteins to the cell surface membrane. Proteins with appropriate C-terminal signal peptides are transferred to the preformed glycolipid anchor in the endoplasmic reticulum and transported to the cell surface as a single unit; in PNH, there is a defect in GPI-anchor biosynthesis and an absence of all surface proteins that use this anchoring motif.
Catalogue number: KTE61212
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: Q07326
Gene: 5281
Additional info: Human Phosphatidylinositol-glycan biosynthesis class F protein (PIGF) ELISA Kit has high sensitivity and excellent specificity for detection of Human PIGF. No significant cross-reactivity or interference between Human PIGF and analogues was observed.

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