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Human Phosphoglucomutase-2 (PGM2) ELISA Kit

Cat no: KTE61226

Human Phosphoglucomutase-2 (PGM2) ELISA Kit

The PGM2 protein shares about 20% identity with mammalian PGM1. Sequence analysis suggested that PGM2 is a cytosolic protein. Quantitative RT-PCR of mouse tissues detected the highest expression levels of PGM2 in lung, spleen, and thymus. PGM2 acted more than 10-fold better as a phosphopentomutasethan as a phosphoglucomutase. PGM2 may play a role in congenital immunodeficiencies. phosphopentomutase uses ribose 1-phosphate and deoxyribose 1-phosphate, which are formed by purine nucleoside phosphorylase and uridine phosphorylase, and that the absence of phosphopentomutase should result in the accumulation of ribose 1-phosphate and deoxyribose 1-phosphate and therefore in a functional block of purine nucleoside phosphorylase.

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SPECIFICATIONS

Catalog Number

KTE61226

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

55276

Accession

Q96G03

Additional Info

Human Phosphoglucomutase-2 (PGM2) ELISA Kit has high sensitivity and excellent specificity for detection of Human PGM2. No significant cross-reactivity or interference between Human PGM2 and analogues was observed.

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