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Human Pituitary tumor-transforming gene 1 protein-interacting protein (PTTG1IP) ELISA Kit

Cat no: KTE61038

Human Pituitary tumor-transforming gene 1 protein-interacting protein (PTTG1IP) ELISA Kit

PTTG1IP, which directly binds to pituitary tumor-transforming gene 1 protein (PTTG1), facilitates the nuclear translocation of PTTG1 and potentiates the transcriptional activation of basic fibroblast growth factor by PTTG1. The gene product localizes to both the cytoplasm and nucleus. Its NLS is required for its own nuclear localization, the nuclear localization of PTTG1, and its interaction with PTTG1.\nThe predicted 180-amino acid C21ORF3 protein has features of a type Ia integral membrane protein and contains the tetrapeptide YXRF, a motif observed in proteins internalized via coated pit-mediated endocytosis. Northern blot analysis detected a 2.69-kb C21ORF3 mRNA in all tissues examined.

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SPECIFICATIONS

Catalog Number

KTE61038

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

754

Accession

P53801

Additional Info

Human Pituitary tumor-transforming gene 1 protein-interacting protein (PTTG1IP) ELISA Kit has high sensitivity and excellent specificity for detection of Human PTTG1IP. No significant cross-reactivity or interference between Human PTTG1IP and analogues was observed.

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