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Human Platelet Factor 4 (PF-4) ELISA Kit

Human Platelet Factor 4 (PF-4) ELISA Kit

Cat no: KTE61246

Supplier: Abbkine Scientific Co.Ltd.
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Platelet factor 4 (PF4) is a small cytokine belonging to the CXC chemokine family. This chemokine is released from alpha-granules of activated platelets during platelet aggregation, and promotes blood coagulation by moderating the effects of heparin-like molecules. Due to these roles, it is predicted to play a role in wound repair and inflammation. It is usually found in a complex with proteoglycan.PF4 is chemotactic for neutrophils, fibroblasts and monocytes, and interacts with a splice variant of the chemokine receptor CXCR3, known as CXCR3B. PF4 is the antigen in heparin-induced thrombocytopenia, an idiosyncratic autoimmune reaction to the administration of the anticoagulant heparin. PF4 autoantibodies have also been found in patients with thrombosis and features resembling HIT but no prior administration of heparin.
Catalogue number: KTE61246
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: P02776
Gene: 5196
Additional info: Human Platelet Factor 4 (PF-4) ELISA Kit has high sensitivity and excellent specificity for detection of Human PF-4. No significant cross-reactivity or interference between Human PF-4 and analogues was observed.

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