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Human Poly ADP ribose polymerase (PARP) ELISA Kit

Human Poly ADP ribose polymerase (PARP) ELISA Kit

Cat no: KTE61302

Supplier: Abbkine Scientific Co.Ltd.
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PARP is a protein involved in a number of cellular processes involving mainly DNA repair and programmed cell death.RP, a 116 kDa nuclear poly (ADP-ribose) polymerase, appears to be involved in DNA repair in response to environmental stress . This protein can be cleaved by many ICE-like caspases in vitroand is one of the main cleavage targets of caspase-3 in vivo . In human PARP, the cleavage occurs between Asp214 and Gly215, which separates the PARP amino-terminal DNA binding domain (24 kDa) from the carboxy-terminal catalytic domain (89 kDa) . PARP1 is a chromatin-associated enzyme, poly-ADP ribose polymerase-1, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. PARP1 has a role in repair of single-stranded DNA (ssDNA) breaks.
Catalogue number: KTE61302
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: P09874
Gene: 142
Additional info: Human Poly ADP ribose polymerase (PARP) ELISA Kit has high sensitivity and excellent specificity for detection of Human PARP1. No significant cross-reactivity or interference between Human PARP1 and analogues was observed.

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