Human Polyserase-2 (PRSS36) ELISA Kit

The deduced 855-amino acid protein has a predicted molecular mass of 93 kD and contains 9 potential N-glycosylation sites. PRSS36 contains a signal peptide, followed by a propeptide domain, an active serine protease domain with the catalytic his, asp, and ser residues, and 2 serine protease domains predicted to be catalytically inactive. The first serine protease domain shares amino acid identity of 40 to 42% with gamma-1 tryptase (TPSG1), pancreasin, matriptase (ST14;), matriptase-2 (TMPRSS6), and polyserase-1 (TMPRSS9). Northern blot analysis detected a 5-kb transcript in fetal kidney and adult skeletal muscle, liver, placenta, and heart. A 2.2-kb transcript was detected in placenta, prostate, and colon and lung adenocarcinoma cell lines, and may be produced by alternative splicing.

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SPECIFICATIONS

Catalog Number

KTE61103

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

146547

Accession

Q5K4E3

Additional Info

Human Polyserase-2 (PRSS36) ELISA Kit has high sensitivity and excellent specificity for detection of Human PRSS36. No significant cross-reactivity or interference between Human PRSS36 and analogues was observed.