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Human PR domain zinc finger protein 8 (PRDM8) ELISA Kit

Human PR domain zinc finger protein 8 (PRDM8) ELISA Kit

Cat no: KTE61184

Supplier: Abbkine Scientific Co.Ltd.
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A family of PRDM proteins are similar to histone methyltransferases (HMTases) with SET domain in that they modulate different cellular processes, including transcriptional regulation, through chromatin modifying activities.In vitro HMTase assay and immunoblot analysis revealed that PRDM8 specifically methylates H3K9 of histones which indicates transcriptional repression activity of PRDM8. Direct recruitment of PRDM8 to the promoter mediated transcriptional repression and indicated no involvement of HDAC. Tissue blot analyses identified PRDM8 transcripts from brain and testis in adult mouse. PRDM8 repressed the expression of steroidogenic markers, p450c17c and LHR, which indicates its regulatory role in mouse testis development.
Catalogue number: KTE61184
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: Q9NQV8
Gene: 56978
Additional info: Human PR domain zinc finger protein 8 (PRDM8) ELISA Kit has high sensitivity and excellent specificity for detection of Human PRDM8. No significant cross-reactivity or interference between Human PRDM8 and analogues was observed.

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