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Human Pre-mRNA-processing factor 6 (PRPF6) ELISA Kit

Cat no: KTE61118


Supplier: Abbkine Scientific Co.Ltd.
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PRP6 appears to be involved in pre-mRNA splicing, possibly acting as a bridging factor between U5 and U4/U6 snRNPs in formation of the spliceosome. The encoded protein also can bind androgen receptor, providing a link between transcriptional activation and splicing. Predicted amino acid sequence of the protein is similar to those of yeast splicing factors, Prp1p/Zer1p of Schizosaccharomyces pombe and Prp6p of Saccharomyces cerevisiae. Among these proteins, tetratrico peptide repeat (TPR) motif, which mediates protein-protein interactions, is conserved, whereas leucine zipper motif is found only in the 100-kDa protein. Indirect immunofluorescent staining showed that the 100-kDa protein localized in the nucleus in HeLa cells.
Catalogue number: KTE61118
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: O94906
Gene: 24148
Additional info: Human Pre-mRNA-processing factor 6 (PRPF6) ELISA Kit has high sensitivity and excellent specificity for detection of Human PRPF6. No significant cross-reactivity or interference between Human PRPF6 and analogues was observed.

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