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Human Prickle-like protein 1 (PRICKLE1) ELISA Kit

Cat no: KTE61162


Supplier: Abbkine Scientific Co.Ltd.
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PRICKLE1 encodes a nuclear receptor that may be a negative regulator of the Wnt/beta-catenin signaling pathway. The encoded protein localizes to the nuclear membrane and has been implicated in the nuclear trafficking of the transcription repressors REST/NRSF and REST4. Mutations in this gene have been linked to progressive myoclonus epilepsy. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 3. The deduced 831-amino acid protein contains 3 N-terminal LIM domains and 3 C-terminal nuclear localization signals. It also contains 4 N-glycosylation sites, 2 PKA phosphorylation sites, and a C-terminal CIIS (cys-ile-ile-ser) prenylation motif. Northern blot analysis detected a single 4.4-kb transcript in all tissues examined, with the highest level in placenta.
Catalogue number: KTE61162
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: Q96MT3
Gene: 144165
Additional info: Human Prickle-like protein 1 (PRICKLE1) ELISA Kit has high sensitivity and excellent specificity for detection of Human PRICKLE1. No significant cross-reactivity or interference between Human PRICKLE1 and analogues was observed.

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