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Human Probable proline dehydrogenase 2 (PRODH2) ELISA Kit

Cat no: KTE61133

Human Probable proline dehydrogenase 2 (PRODH2) ELISA Kit

Probable proline dehydrogenase 2 encoded by PRODH2 catalyzes the first step in the catabolism of trans-4-hydroxy-L-proline, an amino acid derivative obtained through food intake and collagen turnover. One of the downstream products of this catabolism is glyoxylate, which in people with disorders of glyoxalate metabolism can lead to an increase in oxalate levels and the formation of calcium-oxalate kidney stones. Therefore, PRODH2 may serve as a therapeutic target against primary hyperoxalurias (PH). PRODH2 is similar to proline dehydrogenase (oxidase) 1, a mitochondrial enzyme that catalyzes the first step in proline catabolism.

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SPECIFICATIONS

Catalog Number

KTE61133

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

58510

Accession

Q9UF12

Additional Info

Human Probable proline dehydrogenase 2 (PRODH2) ELISA Kit has high sensitivity and excellent specificity for detection of Human PRODH2. No significant cross-reactivity or interference between Human PRODH2 and analogues was observed.

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