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Human Profilin-1 (PFN1) ELISA Kit

Cat no: KTE61241

Human Profilin-1 (PFN1) ELISA Kit

Profilin-1 is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. Deletion of this gene is associated with Miller-Dieker syndrome.\nProfilin is a ubiquitous 12- to 15-kD protein which inhibits the polymerization of actin. It is thought to function by complexing with unpolymerized actin in vivo. Dissociation of the profilin-actin complex is caused by binding of phosphatidylinositol 4,5-bisphosphate to profilin. Ampe et al. (1988) described the amino acid sequence of human platelet profilin and found it to have 95% homology to the sequence of calf spleen profilin.

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SPECIFICATIONS

Catalog Number

KTE61241

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

5216

Accession

P07737

Additional Info

Human Profilin-1 (PFN1) ELISA Kit has high sensitivity and excellent specificity for detection of Human PFN1. No significant cross-reactivity or interference between Human PFN1 and analogues was observed.

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