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Human Programmed cell death protein 6 (PDCD6) ELISA Kit

Cat no: KTE61276


Supplier: Abbkine Scientific Co.Ltd.
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PDCD6 encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant.ALG2 is expressed as a 22-kD protein before FAS activation and thereafter as a 19-kD protein, probably due to N-terminal cleavage. Confocal microscopy and immunoprecipitation analysis demonstrated that ALG2 translocates from the cytoplasmic membrane to the cytosol during FAS-induced apoptosis and then dissociates from FAS after activation.
Catalogue number: KTE61276
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: O75340
Gene: 10016
Additional info: Human Programmed cell death protein 6 (PDCD6) ELISA Kit has high sensitivity and excellent specificity for detection of Human PDCD6. No significant cross-reactivity or interference between Human PDCD6 and analogues was observed.

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