Human Prolactin receptor (PRLR) ELISA Kit

The prolactin receptor-encoded by a gene on Chromosome 5p13-14-interacts with the prolactin molecule as a transmembrane receptor.The 5-prime-untranslated region of the PRLR gene contains 2 alternative first exons: E13, the human counterpart of the rat and mouse E13, and a novel human type of alternative first exon termed E1N. The 5-prime-untranslated region also contains a common noncoding exon 2 and part of exon 3, which contains the translation initiation codon. The E13 and E1N exons are within 800 basepairs of each other. These 2 exons are expressed in human breast tissue, breast cancer cells, gonads, and liver. Overall, the transcript containing E13 is prevalent in most tissues. The PRLR gene product is encoded by exons 3-10, of which exon 10 encodes most of the intracellular domain.

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SPECIFICATIONS

Catalog Number

KTE61142

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

5618

Accession

P16471

Additional Info

Human Prolactin receptor (PRLR) ELISA Kit has high sensitivity and excellent specificity for detection of Human PRLR. No significant cross-reactivity or interference between Human PRLR and analogues was observed.