Human Prolyl endopeptidase (PREP) ELISA Kit

Cat no: KTE61172

Supplier: Abbkine Scientific Co.Ltd.

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Prolyl endopeptidase (PE) also known as prolyl oligopeptidase or post-proline cleaving enzyme is an enzyme that in humans is encoded by the PREP gene.Prolyl endopeptidase is a large cytosolic enzyme that belongs to a distinct class of serine peptidases. It was first described in the cytosol of rabbit brain as an oligopeptidase, which degrades the nonapeptide bradykinin at the Pro-Phe bond.[5] The enzyme is involved in the maturation and degradation of peptide hormones and neuropeptides such as alpha-melanocyte-stimulating hormone, luteinizing hormone-releasing hormone (LH-RH), thyrotropin-releasing hormone, angiotensin, neurotensin, oxytocin, substance P and vasopressin. PREP cleaves peptide bonds at the C-terminal side of proline residues. Its activity is confined to action on oligopeptides of less than 10 kD and it has an absolute requirement for the trans-configuration of the peptide bond preceding proline. Prolyl endopeptidases are involved in the maturation and degradation of peptide hormones and neuropeptides.

Catalogue number:	KTE61172
Reactivities:	Human
Applications:	ELISA
Size:	48T, 96T, 96T5, 96T50
Accession:	P48147
Gene:	5550
Additional info:	Human Prolyl endopeptidase (PREP) ELISA Kit has high sensitivity and excellent specificity for detection of Human PREP. No significant cross-reactivity or interference between Human PREP and analogues was observed.

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Human Prolyl endopeptidase (PREP) ELISA Kit

Cat no: KTE61172

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