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Human Proprotein convertase subtilisin/kexin type 9 (PCSK9) ELISA Kit

Human Proprotein convertase subtilisin/kexin type 9 (PCSK9) ELISA Kit

Cat no: KTE61285

Supplier: Abbkine Scientific Co.Ltd.
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PCSK9 belonging to the proteinase K subfamily of the secretory subtilase family. The encoded protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. This protein plays a major regulatory role in cholesterol homeostasis. PCSK9 binds to the epidermal growth factor-like repeat A (EGF-A) domain of the low-density lipoprotein receptor (LDLR), inducing LDLR degradation. Reduced LDLR levels result in decreased metabolism of low-density lipoproteins, which could lead to hypercholesterolemia. Inhibition of PSCK9 function is currently being explored as a means of lowering cholesterol levels. PCSK9 may also have a role in the differentiation of cortical neurons.
Catalogue number: KTE61285
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: Q8NBP7
Gene: 255738
Additional info: Human Proprotein convertase subtilisin/kexin type 9 (PCSK9) ELISA Kit has high sensitivity and excellent specificity for detection of Human PCSK9. No significant cross-reactivity or interference between Human PCSK9 and analogues was observed.

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