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Human Prostacyclin receptor (PTGIR) ELISA Kit

Human Prostacyclin receptor (PTGIR) ELISA Kit

Cat no: KTE61070

Supplier: Abbkine Scientific Co.Ltd.
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Prostacyclin receptor is a member of the G-protein coupled receptor family. Prostacyclin, the major product of cyclooxygenase in macrovascular endothelium, elicits a potent vasodilation and inhibition of platelet aggregation through binding to this receptor. When binding a prostacyclin-molecule, the receptor changes conformation and activates Gs, with its activation of cAMP and increase in protein kinase A (PKA) activity.In vasodilation, the PKA activity causes phosphorylation of MLCK, decreasing its activity, resulting in dephosphorylation of MLC of myosin. The smooth muscle relaxation leads to vasodilation.
Catalogue number: KTE61070
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: P43119
Gene: 5739
Additional info: Human Prostacyclin receptor (PTGIR) ELISA Kit has high sensitivity and excellent specificity for detection of Human PTGIR. No significant cross-reactivity or interference between Human PTGIR and analogues was observed.

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