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Human Proteasome activator complex subunit 3 (PSME3) ELISA Kit

Human Proteasome activator complex subunit 3 (PSME3) ELISA Kit

Cat no: KTE61080

Supplier: Abbkine Scientific Co.Ltd.
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The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. This gene encodes the gamma subunit of the 11S regulator. Six gamma subunits combine to form a homohexameric ring. Two transcript variants encoding different isoforms have been identified.
Catalogue number: KTE61080
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: P61289
Gene: 10197
Additional info: Human Proteasome activator complex subunit 3 (PSME3) ELISA Kit has high sensitivity and excellent specificity for detection of Human PSME3. No significant cross-reactivity or interference between Human PSME3 and analogues was observed.

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