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Human [Protein ADP-ribosylarginine] hydrolase (ADPRH) ELISA Kit

Cat no: KTE60946

Human [Protein ADP-ribosylarginine] hydrolase (ADPRH) ELISA Kit

The deduced human ADPRH protein has 357 amino acids and an estimated molecular mass of 39.5 kD. Human ADPRH shows 83% amino acid identity to rat Adprh and 82% identity to mouse Adprh. The authors found that the mouse and rat Adprh sequences contain 5 conserved cysteine residues; the human sequence contains only 4 cysteines, with cys108 in rat corresponding to ser103 in human.\nExpression of recombinant wildtype and mutant rat and human ADPRH proteins in E. coli and assessment of their DTT requirements for hydrolase activity demonstrated that cys108 is responsible for the DTT dependence of rat Adprh. Northern blot analysis detected a 4.1-kb ADPRH transcript in various human tissues, including fetal and adult brain.

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SPECIFICATIONS

Catalog Number

KTE60946

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

141

Accession

P54922

Additional Info

Human [Protein ADP-ribosylarginine] hydrolase (ADPRH) ELISA Kit has high sensitivity and excellent specificity for detection of Human ADPRH. No significant cross-reactivity or interference between Human ADPRH and analogues was observed.

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