Human Protein disulfide-isomerase A6 (PDIA6) ELISA Kit

Cat no: KTE61261

Supplier: Abbkine Scientific Co.Ltd.

0 reviews | Write a Review Pencil

Read More on Supplier Website

Description
Additional Information

Protein disulfide isomerases, such as PDIA6, are endoplasmic reticulum resident proteins that catalyze formation, reduction, and isomerization of disulfide bonds in proteins and are thought to play a role in folding of disulfide-bonded proteins The deduced 440-amino acid protein has a calculated molecular mass of 48.1 kD. It has a putative N-terminal signal sequence, followed by 2 thioredoxin like domains and a C-terminal ER retention signal. Mutation analysis revealed that the first thioredoxin-like motif of P5 was more important than the second for isomerase activity, and that the first cysteine in each motif was necessary for isomerase activity. Thioredoxin motif mutants of P5 lacking isomerase activity retained chaperone activity with citrate synthase as substrate, indicating that, like PDI, the isomerase and chaperone activities of P5 are likely independent.

Catalogue number:	KTE61261
Reactivities:	Human
Applications:	ELISA
Size:	48T, 96T, 96T5, 96T50
Accession:	Q15084
Gene:	10130
Additional info:	Human Protein disulfide-isomerase A6 (PDIA6) ELISA Kit has high sensitivity and excellent specificity for detection of Human PDIA6. No significant cross-reactivity or interference between Human PDIA6 and analogues was observed.

See Full Product Listings >

Human Protein disulfide-isomerase A6 (PDIA6) ELISA Kit

Cat no: KTE61261

Get Quote

About Biosave

Product Categories

Information


Get a Quote Direct from Abbkine Scientific Co.Ltd.




By submitting this form you agree to your details being passed to Abbkine Scientific Co.Ltd. for the purpose of generating the best quote*