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Human Protein-L-isoaspartate (PCMT1) ELISA Kit

Human Protein-L-isoaspartate (PCMT1) ELISA Kit

Cat no: KTE61292

Supplier: Abbkine Scientific Co.Ltd.
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Three classes of protein carboxyl methyltransferases, distinguished by their methyl-acceptor substrate specificity, have been found in prokaryotic and eukaryotic cells. The type II enzyme catalyzes the transfer of a methyl group from S-adenosyl-L-methionine to the free carboxyl groups of D-aspartyl and L-isoaspartyl residues. These methyl-accepting residues result from the spontaneous deamidation, isomerization, and racemization of normal L-aspartyl and L-asparaginyl residues and represent sites of covalent damage to aging proteins PCMT1 (EC 2.1.1.77) is a protein repair enzyme that initiates the conversion of abnormal D-aspartyl and L-isoaspartyl residues to the normal L-aspartyl form.
Catalogue number: KTE61292
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: P22061
Gene: 5110
Additional info: Human Protein-L-isoaspartate (PCMT1) ELISA Kit has high sensitivity and excellent specificity for detection of Human PCMT1. No significant cross-reactivity or interference between Human PCMT1 and analogues was observed.

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