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Human Protein quaking (QKI) ELISA Kit

Human Protein quaking (QKI) ELISA Kit

Cat no: KTE61006

Supplier: Abbkine Scientific Co.Ltd.
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QKI belongs to a family of RNA-binding proteins called STAR proteins for Signal Transduction and Activation of RNA. They have an HNRNPK homology (KH) domain embedded in a 200-amino acid region called the GSG domain. Other members of this family include SAM68 (KHDRBS1) and SF1. The QKI gene is implicated as being important in schizophrenia, and QKI controls translation of many oligodendrocyte-related genes.The balance between the nuclear and cytoplasmic isoforms of Qk1 controlled the nuclear export of Mbp mRNAs and the cellular localization of the 17- and 21.5-kD Mbp isoforms. Overexpression of Qki-5 in cultured rodent oligodendrocytes recreated the Mbp defects observed in qk(v) mice, with retention of Mbp in the nucleus.
Catalogue number: KTE61006
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: Q96PU8
Gene: 9444
Additional info: Human Protein quaking (QKI) ELISA Kit has high sensitivity and excellent specificity for detection of Human QKI. No significant cross-reactivity or interference between Human QKI and analogues was observed.

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