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Human Protein S100-A7A (S100A7A) ELISA Kit

Cat no: KTE60761

Human Protein S100-A7A (S100A7A) ELISA Kit

The human calcium-binding protein (hS100A15) was first identified in inflamed hyperplastic psoriatic skin, where the S100A15 gene is transcribed into two mRNA splice variants, hS100A15-S and hS100A15-L. In cultured keratinocytes, IL-1beta and Th1 cytokines significantly induced hS100A15-L compared with hS100A15-S. In contrast, Th2-derived cytokines had no influence on the expression of either hS100A15 splice variant. Differentiation of human keratinocytes induced by 1.2 mm calcium resulted in the upregulation of both hS100A15 mRNA isoforms. Overexpression of hS100A15 in chronic inflammatory skin diseases and regulation by inflammatory cytokines and calcium suggest that hS100A15 is involved in Th1-associated epithelial responses and epidermal maturation in normal and diseased human skin.

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SPECIFICATIONS

Catalog Number

KTE60761

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

338324

Accession

Q86SG5

Additional Info

Human Protein S100-A7A (S100A7A) ELISA Kit has high sensitivity and excellent specificity for detection of Human S100A7A. No significant cross-reactivity or interference between Human S100A7A and analogues was observed.

SUPPLIER INFO

Abbkine Scientific Co.Ltd.

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