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Human Protein Tob1 (TOB1) ELISA Kit

Cat no: KTE60171

Human Protein Tob1 (TOB1) ELISA Kit

TOB1 encodes a member of the tob/btg1 family of anti-proliferative proteins that have the potential to regulate cell growth. When exogenously expressed, this protein supresses cell growth in tissue culture.\nThe protein undergoes phophorylation by a serine/threonine kinase, 90 kDa ribosomal S6 kinase. Interactions of this protein with the v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 gene product p185 interferes with growth suppression. This protein inhibits T cell proliferation and transcription of cytokines and cyclins. The protein interacts with both mothers against decapentaplegic Drosophila homolog 2 and 4 to enhance their DNA binding activity. This interaction inhibits interleukin 2 transcription in T cells.

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SPECIFICATIONS

Catalog Number

KTE60171

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

10140

Accession

P50616

Additional Info

Human Protein Tob1 (TOB1) ELISA Kit has high sensitivity and excellent specificity for detection of Human TOB1. No significant cross-reactivity or interference between Human TOB1 and analogues was observed.

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