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Human Protein tyrosine phosphatase 1B (PTP1B) ELISA Kit

Cat no: KTE61052

Human Protein tyrosine phosphatase 1B (PTP1B) ELISA Kit

Tyrosine-protein phosphatase non-receptor type 1 is the founding member of the protein tyrosine phosphatase (PTP) family, which was isolated and identified based on its enzymatic activity and amino acid sequence. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity.\nPTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP has been shown to act as a negative regulator of insulin signaling by dephosphorylating the phosphotryosine residues of insulin receptor kinase.

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SPECIFICATIONS

Catalog Number

KTE61052

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

5770

Accession

P18031

Additional Info

Human Protein tyrosine phosphatase 1B (PTP1B) ELISA Kit has high sensitivity and excellent specificity for detection of Human PTPN1. No significant cross-reactivity or interference between Human PTPN1 and analogues was observed.

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