Human Protein tyrosine phosphatase type IVA 3 (PTP4A3) ELISA Kit

Protein tyrosine phosphatase type IVA 3 is an enzyme belongs to a small class of prenylated protein tyrosine phosphatases (PTPs). PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This class of PTPs contain a PTP domain and a characteristic C-terminal prenylation motif. Studies of this class of PTPs in mice demonstrated that they were prenylated proteins in vivo, which suggested their association with cell plasma membrane. Overexpression of this gene in mammalian cells was reported to inhibit angiotensin-II induced cell calcium mobilization and promote cell growth. Two alternatively spliced variants exist.Mainly expressed in cardiomyocytes and skeletal muscle; also found in pancreas. Consistently overexpressed in colon cancer metastasis.

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SPECIFICATIONS

Catalog Number

KTE61055

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

11156

Accession

O75365

Additional Info

Human Protein tyrosine phosphatase type IVA 3 (PTP4A3) ELISA Kit has high sensitivity and excellent specificity for detection of Human PTP4A3. No significant cross-reactivity or interference between Human PTP4A3 and analogues was observed.