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Human RAC-alpha serine/threonine-protein kinase (AKT1) ELISA Kit

Cat no: KTE60641


Supplier: Abbkine Scientific Co.Ltd.
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The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery.
Catalogue number: KTE60641
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: P31749
Gene: 207
Additional info: Human RAC-alpha serine/threonine-protein kinase (AKT1) ELISA Kit has high sensitivity and excellent specificity for detection of Human AKT1. No significant cross-reactivity or interference between Human AKT1 and analogues was observed.

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