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Human RAC-beta serine/threonine-protein kinase (AKT2) ELISA Kit

Human RAC-beta serine/threonine-protein kinase (AKT2) ELISA Kit

Cat no: KTE60642

Supplier: Abbkine Scientific Co.Ltd.
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AKT2 is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phosphorylating several known proteins. Mice lacking Akt2 have a normal body mass, but display a profound diabetic phenotype, indicating that Akt2 plays a key role in signal transduction downstream of the insulin receptor. Mice lacking Akt2 show worse outcome in breast cancer initaited by the large T antigen as well as the neu oncogene.
Catalogue number: KTE60642
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: P31751
Gene: 208
Additional info: Human RAC-beta serine/threonine-protein kinase (AKT2) ELISA Kit has high sensitivity and excellent specificity for detection of Human AKT2. No significant cross-reactivity or interference between Human AKT2 and analogues was observed.

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