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Human Ras-related C3 botulinum toxin substrate 1 (RAC1) ELISA Kit

Human Ras-related C3 botulinum toxin substrate 1 (RAC1) ELISA Kit

Cat no: KTE60987

Supplier: Abbkine Scientific Co.Ltd.
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Rac1 is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for this gene. This mutant did bind to POR1 and it induced membrane ruffling and transformation. A second RAC mutant, which bound PAK but not POR1, induced JNK activation but was defective in inducing membrane ruffling and transformation. The authors concluded that the effects of RAC on the JNK cascade and on actin polymerization and cell proliferation are mediated by distinct effector functions that diverge at the level of RAC itself.
Catalogue number: KTE60987
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: P63000
Gene: 5879
Additional info: Human Ras-related C3 botulinum toxin substrate 1 (RAC1) ELISA Kit has high sensitivity and excellent specificity for detection of Human RAC1. No significant cross-reactivity or interference between Human RAC1 and analogues was observed.

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