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Human Ras-related protein Rab-3B (RAB3B) ELISA Kit

Cat no: KTE60991


Supplier: Abbkine Scientific Co.Ltd.
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The mammalian RAB proteins show striking similarities to the S. cerevisiae YPT1 and SEC4 proteins, Ras-related GTP-binding proteins involved in the regulation of secretion.RAB3B protein shares 78% identity with RAB3A. After endocytosis, the PIGR-dIgA complex traverses several endosomal compartments and is exocytosed at the apical plasma membrane Rab3b localized to vesicular structures containing Pigr in canine kidney cells and that GTP-bound Rab3b interacted directly with the cytoplasmic domain of Pigr. Binding of dIgA to Pigr dissociated Rab3b, but a constitutively active Rab3b mutant maintained its interaction with Pigr in dIgA-treated cells. Furthermore, GTP-locked Rab3b inhibited dIgA-stimulated transcytosis.
Catalogue number: KTE60991
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: P20337
Gene: 5865
Additional info: Human Ras-related protein Rab-3B (RAB3B) ELISA Kit has high sensitivity and excellent specificity for detection of Human RAB3B. No significant cross-reactivity or interference between Human RAB3B and analogues was observed.

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