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Human Receptor for advanced glycation end products (RAGE/AGER) ELISA Kit

Human Receptor for advanced glycation end products (RAGE/AGER) ELISA Kit

Cat no: KTE60960

Supplier: Abbkine Scientific Co.Ltd.
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RAGE, the receptor for advanced glycation endproducts is a 35kD transmembrane receptor of the immunoglobulin super family which was first characterized in 1992 by Neeper et al.. Its name comes from its ability to bind advanced glycation endproducts (AGE), a heterogeneous group of non-enzymatically altered proteins. Besides AGEs, RAGE is also able to bind other ligands and is thus often referred to as a pattern recognition receptor.The interaction between RAGE and its ligands is thought to result in pro-inflammatory gene activation. Due to an enhanced level of RAGE ligands in diabetes or other chronic disorders, this receptor is hypothesised to have a causative effect in a range of inflammatory diseases such as diabetic complications, Alzheimer's disease and even some tumors.
Catalogue number: KTE60960
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: Q15109
Gene: 177
Additional info: Human Receptor for advanced glycation end products (RAGE/AGER) ELISA Kit has high sensitivity and excellent specificity for detection of Human AGER. No significant cross-reactivity or interference between Human AGER and analogues was observed.

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