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Human Retinoic acid receptor responder protein 1 (RARRES1) ELISA Kit

Cat no: KTE60975

Human Retinoic acid receptor responder protein 1 (RARRES1) ELISA Kit

RARRES1 was identified as a retinoid acid (RA) receptor-responsive gene. It encodes a type 1 membrane protein. The expression of this gene is upregulated by tazarotene as well as by retinoic acid receptors. The expression of this gene is found to be downregulated in prostate cancer, which is caused by the methylation of its promoter and CpG island. Alternatively spliced transcript variant encoding distinct isoforms have been observed.Strong RARRES1 expression could be induced by RAR-specific but not RXR-specific agents. In situ hybridization analysis showed that treatment of psoriatic rafts or patient skin lesions with tazarotene induces RARRES1 expression. Nonlesional and sham-treated lesional psoriatic skin showed no expression of RARRES1.

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SPECIFICATIONS

Catalog Number

KTE60975

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

5918

Accession

P49788

Additional Info

Human Retinoic acid receptor responder protein 1 (RARRES1) ELISA Kit has high sensitivity and excellent specificity for detection of Human RARRES1. No significant cross-reactivity or interference between Human RARRES1 and analogues was observed.

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