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Human Retinoic acid receptor responder protein 2 (RARRES2) ELISA Kit

Cat no: KTE60974

Human Retinoic acid receptor responder protein 2 (RARRES2) ELISA Kit

Chemerin is a novel protein identified as the natural ligand of ChemR23 (chemerinR), a previously orphan G protein-coupled receptor expressed in immature dendritic cells and macrophages. It is a member of the Cystatin superfamily. Chemerin is synthesized as a 163 aa secreted precursor, prochemerin, which contains a hydrophobic 20 aa N-terminal sequence, an intervening 137 aa Cystatin fold-containing domain, and a six aa C-terminal prosegment. It is activated by proteases of the coagulation, fibrinolytic, and inflammatory cascades and converted into a full agonist of chemerinR by proteolytic removal of the last six amino acids.Chemerin is a chemoattractant for cells bearing the Chem R23 receptor, including plasmacytoid dendritic cells and tissue macrophages.

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SPECIFICATIONS

Catalog Number

KTE60974

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Additional Info

Human Retinoic acid receptor responder protein 2 (RARRES2) ELISA Kit has high sensitivity and excellent specificity for detection of Human RARRES2. No significant cross-reactivity or interference between Human RARRES2 and analogues was observed.

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