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Human Ribonucleases P/MRP protein subunit POP1 (POP1) ELISA Kit

Human Ribonucleases P/MRP protein subunit POP1 (POP1) ELISA Kit

Cat no: KTE61196

Supplier: Abbkine Scientific Co.Ltd.
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POP1 is a protein subunit of two different small nucleolar ribonucleoprotein complexes: the endoribonuclease for mitochondrial RNA processing complex and the ribonuclease P complex. This protein is a ribonuclease that localizes to the nucleus and functions in pre-RNA processing.Human POP1 encodes a predicted 1,024-amino acid protein that has a pI of 9.86. On Northern blots, human POP1 is expressed as a major 4.1-kb and minor 6-kb transcript, perhaps due to alternative polyadenylation signals. Anti-POP1 antibodies recognize a doublet of approximately 115 kD on Western blots. In HeLa cells, human POP1 localizes to the nucleus and strongly accumulates in the nucleolus. In co-immunoprecipitation studies, POP1 was associated with both RNase P and RNase MRP snRNAs, and with RNase P enzymatic activity.
Catalogue number: KTE61196
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: Q99575
Gene: 10940
Additional info: Human Ribonucleases P/MRP protein subunit POP1 (POP1) ELISA Kit has high sensitivity and excellent specificity for detection of Human POP1. No significant cross-reactivity or interference between Human POP1 and analogues was observed.

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