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Human Runt-related transcription factor 3 (RUNX3) ELISA Kit

Human Runt-related transcription factor 3 (RUNX3) ELISA Kit

Cat no: KTE60776

Supplier: Abbkine Scientific Co.Ltd.
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RUNX3 is a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene. Runx3 mouse gastric mucosa exhibits hyperplasia due to stimulated proliferation and suppressed apoptosis in epithelial cells, and the cells are resistant to TGF-beta stimulation.
Catalogue number: KTE60776
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: Q13761
Gene: 864
Additional info: Human Runt-related transcription factor 3 (RUNX3) ELISA Kit has high sensitivity and excellent specificity for detection of Human RUNX3. No significant cross-reactivity or interference between Human RUNX3 and analogues was observed.

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